Allergy Contraindicated Do not use if you are allergic to Mecobalamin or Pyridoxine or Nicotinamide, or any other ingredients
Once you hit the 6-month period, or 6 total refills, take a break from B12/MIC for a minimum of 3 months
European Journal of Endocrinology , 143(4), 535541
For example, PLP is required for the synthesis of neurotransmitters such as GABA and serotonin, for heme biosynthesis (through -amino levulinate synthase in red blood cell production), and for amino acid transformations
Possible adverse effects may include: Injection site reactions : Redness, swelling, irritation, or discomfort Gastrointestinal symptoms : Nausea, vomiting, stomach cramps, or diarrhea Headaches or dizziness Allergic reactions : Rash, itching, shortness of breath, or facial swelling (rare) Increased heart rate or anxiety (typically temporary from B-vitamins) Fatigue or weakness if used improperly Elevated liver enzymes when taken in excess particularly with methionine or choline Insomnia if taken late in the day due to increased energy levels Who should avoid or use caution
